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Consultant Dr. med. Zina-Mary Manjaly

Dr. med. Zina-Mary Manjaly Spezialistin Neurologie

Dr Manjaly is a neurology specialist who completed her clinical training in England and Switzerland. She is a clinical scientist at ETH Zurich, specialising in fatigue, multiple sclerosis and brain imaging techniques (neuroimaging). Building on her Master’s degree in Mindfulness-Based Cognitive Therapy (MBCT) from the University of Oxford, she is also investigating the role of cognitive factors in neurological symptoms and therapeutic efficacy.

Position and faculty

Consultant Neurology

To the department Neurology



Multiple sclerosis

Mindfulness-Based Cognitive Therapy (MBCT)





Phone hours
Mo–Th 08.00–17.00
Fr 08.00–16.00
Sa–Su Closed

Medical specialisation


Certificates of proficiency

Electroneuromyography (ENMG)

Electroencephalography (EEG)

Cerebrovascular diseases


since 2018

Special consultation for Fatigue at Schulthess Klinik

since 2015

Schulthess Klinik


Clinic for Neurology, Universitätsspital Zürich


Clinic for Psychiatry, Universitätsspital Zürich


Clinic for Internal Medicine, Universitätsspital Zürich


Clinic for Neurology, Universitätsspital Zürich


Maidstone Hospital (Teaching hospital of the King’s College London), Internal Medicine, Emergency Medicine, Psychiatry

Education and training


Master of Studies (MSt), University of Oxford


Specialist in Neurology FMH


Dr. med., University of Aachen (summa cum laude)


State Examination, Heinrich-Heine-Universität Düsseldorf

Scientific activities


since 2020: MCBT in Psychiatry & Computational Psychiatry, Bachelor of Human Medicine ETH Zurich 

since 2019: Sensomotor functions of the spinal cord, Bachelor of Human Medicine ETH Zurich 

2018 Lecture "Mindfulness-Based Cognitive Therapy", Association for Further Education in Psychiatry and Psychotherapy (WBV) for prospective specialists in psychiatry

since 2017 Lecture "Cerebellum", Bachelor Human Medicine ETH Zurich

since 2017 Neurological examination course, Bachelor of Human Medicine ETH Zurich


Scientific focus

  • Fatigue
  • Multiple Sklerosis
  • Brain imaging (neuroimaging), especially functional MRI
  • Mindfulness-Based Cognitive Therapy (MBCT)


  • ETH Zurich
  • Universitätsspital Zürich
  • University College London

Expert activities

  • NeuroImage Clinical
  • Swiss Multiple Sclerosis Society


Swiss Society of Clinical Neurophysiology SGKN

Neurological Society of the Canton of Zurich ZNG

Swiss Medical Association FMH

Swiss Neurological Society SNG

International Multiple Sclerosis Cognition Society IMSCOGS

Awards and honours

2008 Friedrich-Wilhelm prize (promotion award RWTH Aachen)

2007 Borchers badge (RWTH Aachen)

2006 Günther-Leibfried prize (Research centre Jülich)

2005 International NRW Undergraduate Science Award (Ministry of Science NRW)

Grants and stipends

2004–2006 Scholar of the German National Academic Foundation

2003 Travel Award from Allianz Insurance for a stay abroad at Oxford University

2003 Study delegate of the Helmholtz Association at the Nobel Laureate Meeting, Lindau

1997 Honour Roll Award (Board of Education, Toronto, Kanada)


Artikel in internationalen Zeitschriften mit Gutachtersystem

Frässle S, Manjaly ZM, Do CT, Kasper L, Pruessmann KP, Stephan KE. Whole-brain estimates of directed connectivity for human connectomicsNeuroimage. 2020 Oct 24;225:117491. doi: 10.1016/j.neuroimage.2020.117491.

Do CT*, Manjaly ZM”, Heinzle J, Schöbi D, Kasper L, Pruessmann KP, Stephan KE, Frässle S. (“shared first authorship) Hemodynamic modeling of long-term aspirin effects on blood oxygenated level dependent responses at 7 Tesla in patients at cardiovascular risk. Eur J Neurosci. 2020 Sep 16. doi: 10.1111/ejn.14970. Online ahead of print.

Zina-Mary Manjaly and Sandra Iglesias (2020), A Computational Theory of Mindfulness Based Cognitive Therapy from the “Bayesian Brain” Perspective. Front. Psychiatry 11:404. doi: 10.3389/fpsyt.2020.00404

Marco Kaufmann, Anke Salmen, Laura Barin, Milo Alan Puhan, Pasquale Calabrese, Christian Philipp Kamm, Claudio Gobbi, Jens Kuhle, Zina-Mary Manjaly, Vladeta Ajdacic-Gross, Sandra Schafroth, Britta Bottignole, Sabin Ammann, Chiara Zecca, Marcus D'Souza, Viktor von Wyl, for the Swiss Multiple Sclerosis Registry (SMSR) (2020), Development and validation of the self-reported disability status scale (SRDSS) to estimate EDSS-categories. Multiple Sclerosis and Related Disorders 42,  102148,

Articles in international journals with review system

Manjaly ZM, Harrison NA, Critchley H, Do CT, Stefanics G, Wenderoth N, Lutterotti A, Müller A, Stephan KE (2019) Pathophysiological and Cognitive Mechanisms of Fatigue in Multiple Sclerosis. Journal of Neurology, Neurosurgery, and Psychiatry, in press. doi:10.1136/jnnp-2018-32005

Manjaly ZM, Harrison NA, Critchley H, Do CT, Stefanics G, Wenderoth N, Lutterotti A, Müller A, Stephan KE (2019) Pathophysiological and Cognitive Mechanisms of Fatigue in Multiple Sclerosis. Journal of Neurology, Neurosurgery, and Psychiatry, in press. doi:10.1136/jnnp-2018-32005

Frässle S, Lomakina E, Kasper L, Manjaly ZM, Leff A, Pruessmann KP, Buhmann JM, Stephan KE (2018) A generative model of whole-brain effective connectivity. Neuroimage 179: 505-529

Kasper L, Bollmann S, Diaconescu AO, Hutton C, Heinzle J, Iglesias S, Hauser TU, Sebold M, Manjaly ZM, Pruessmann KP, Stephan KE (2017) The PhysIO Toolbox for Modeling Physiological Noise in fMRI Data. Journal of Neuroscience Methods 276: 56-72

Stephan KE, Manjaly ZM, Mathys CD, Weber LA, Paliwal S, Gard T, Tittgemeyer M, Fleming SM, Haker H, Seth AK, Petzschner FH (2016) Allostatic Self-efficacy: A Metacognitive Theory of Dyshomeostasis-Induced Fatigue and Depression. Frontiers Human Neuroscience 10: 550.

Manjaly ZM, Luft AL, Sarikaya H (2011) An unusual cause of pseudo-median nerve palsy. Case Reports in Neurological Medicine Article ID 474271. doi:10.1155/2011/474271

Manjaly ZM, Bruning N, Neufang S, Stephan KE, Brieber S, Marshall JC, Konrad K, Kamp-Becker I, Remschmidt H, Herpertz-Dahlmann B, Fink GR (2007) Neurophysiological correlates of relatively enhanced local visual search in autistic adolescents. NeuroImage 35: 283-291.

Manjaly ZM, Marshall JC, Stephan KE, Gurd JM, Zilles K, Fink GR (2005) Context-dependent interaction of the left posterior inferior frontal gyrus in a local visual search task unrelated to language. Cognitive Neuropsychology 22: 292-305.

Manjaly ZM, Marshall JC, Stephan KE, Gurd JM, Zilles K, Fink GR (2003) In search of the hidden: an fMRI study with implications for the study of patients with autism and with acquired brain injury. NeuroImage 19: 674-683.

Invited articles (without review)

Manjaly ZM (2018) Fatigue bei rheumatoider Arthritis. SPV/ASP – info 150: 5-14

Manjaly ZM (2018) Diagnostik und Therapie der Fatigue bei Multipler Sklerose. Schweizer Zeitschrift für Neurologie und Psychiatrie 3: 28-30

Book chapters

Fink GR, Manjaly ZM, Stephan KE, Gurd JM, Zilles K, Amunts K, Marshall JC (2006) A role for Broca’s area beyond language processing: evidence from neuropsychology and fMRI. In: Broca’s Region (ed. Grodzinsky Y, Amunts K), pp. 254-270. Oxford: Oxford University Press.